Liver cells have an innate resistance to RNA viral infections like hepatitis A, dengue and Zika thanks to a protein called IRF1, according to researchers at the University of North Carolina at Chapel Hill (UNC) and Tokyo Metropolitan Institute of Medical Science (TMIMS). When present in liver cells, this IRF1 protein regulates RARRES3, an enzyme that when expressed in cells where hepatitis A virus is trying to set up shop, will attack the virus. These results were published in Nature Microbiology.
From https://medicalxpress.com/news/2019-04-liver-cells-viral.html
from
https://healthnews010.wordpress.com/2019/04/16/researchers-identify-how-liver-cells-protect-against-viral-attacks/
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