Calorie Restriction Affects the Plasticity of Fat Tissue, Not Just the Amount of Fat Tissue

The practice of calorie restriction, a reduction of up to 40% below the usual ad libitum calorie intake, while still obtaining optimal levels of dietary micronutrients, is well known to slow aging and extend life in near all species and lineages tested to date. Calorie restriction produces sweeping changes in the operation of cellular metabolism, such as upregulation of a range of cellular stress responses, including the maintenance processes of autophagy. It also, however, has the obvious outcome of greatly reducing body fat, particularly the visceral fat that clusters around the organs of the abdomen. Visceral fat tissue is metabolically active and quite harmful over the long term, so there is always the question of the degree to which the benefits of calorie restriction derive from loss

From https://www.fightaging.org/archives/2019/04/calorie-restriction-affects-the-plasticity-of-fat-tissue-not-just-the-amount-of-fat-tissue/

from
https://healthnews010.wordpress.com/2019/04/16/calorie-restriction-affects-the-plasticity-of-fat-tissue-not-just-the-amount-of-fat-tissue/